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[通过放射免疫测定法和放射受体测定法测量大鼠血管活性肠肽(VIP)的组织分布(作者译)]

[Vasoactive intestinal polypeptide (VIP) tissue distribution in the rat as measured by radioimmunoassay and by radioreceptorassay (author's transl)].

作者信息

Besson J, Dupont C, Laburthe M, Bataille D, Rosselin G

出版信息

Ann Endocrinol (Paris). 1977 Mar-Apr;38(2):145-6.

PMID:900867
Abstract

A new radioimmunoassay which allows the measurement of the rat vasoactive intestinal polypeptide, was performed. VIP is present in the whole digestive tract of rat, mainly between the duodenum and the colon. 1.5% of the total VIP is present in brain. The VIP-like immunoreactivity appears to correspond to biologically active molecule since a radioreceptorassay using liver plasma membranes as the target tissue, gives the same results as the radioimmunoassay.

摘要

开展了一项新的放射免疫测定法,用于测定大鼠血管活性肠肽。血管活性肠肽存在于大鼠整个消化道中,主要位于十二指肠和结肠之间。血管活性肠肽总量的1.5%存在于大脑中。由于以肝细胞膜作为靶组织的放射受体测定法与放射免疫测定法结果相同,因此血管活性肠肽样免疫反应性似乎对应于生物活性分子。

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