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三例嗜铬细胞瘤患者的肾素血浆活性和血浆醛固酮(作者译)

[Renin plasmatic activity and plasma aldosterone in three cases of pheochromocytoma (author's transl)].

作者信息

Ménagé J J, Loubrieu G, Besnard J C, Néel J L

出版信息

Ann Endocrinol (Paris). 1977 Mar-Apr;38(2):161-2.

PMID:900871
Abstract

Renin Plasmatic Activity (R.P.A.) was increased in three cases of Pheochromocytoma Plasmatic aldosterone (A), measured in one patient, was high in the supine position and increased considerably in orthostatism. This was not observed with the R.P.A.7. Urine Tetra Hydroaldosterone (T.H.A.) was increased in two of the three patients and this increase corresponded to the Pheochromocytoma in which the V.M.A. concentrations were the highest. P.R.A., T.H.A. and V.M.A. regained normal values after surgery. We suggest that there is a certain parrallelism between the increase in the excretion of A. and the importance of the catécholamine release from the Pheocchromocytoma.

摘要

三例嗜铬细胞瘤患者的肾素血浆活性(R.P.A.)升高。在一名患者中检测的血浆醛固酮(A),仰卧位时较高,直立位时显著升高。而肾素血浆活性(R.P.A.)未观察到这种情况。三名患者中有两名患者的尿四氢醛固酮(T.H.A.)升高,且这种升高与香草扁桃酸(V.M.A.)浓度最高的嗜铬细胞瘤相对应。术后肾素活性(P.R.A.)、四氢醛固酮(T.H.A.)和香草扁桃酸(V.M.A.)恢复正常。我们认为,醛固酮(A)排泄增加与嗜铬细胞瘤释放儿茶酚胺的程度之间存在一定的平行关系。

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