Abraham A A, Manko M A
Arch Intern Med. 1977 Sep;137(9):1198-1200.
Fatal disseminated herpesvirus hominis type 2 infection developed in a 24-year-old woman with psychiatric disease. The primary site of virus entry appeared to be the upper respiratory tract, although the cervix and anus could have been primary sites. Dissemination of infection was facilitated by steroid therapy. An endotracheal tube may have increased spread to the lower respiratory tract and an intrauterine device may have aided spread to the uterus. Intranuclear inclusion body-bearing cells in the respiratory secretions should alert the clinician to possible herpesvirus disease, local and disseminated, even in the nonimmunecompromised patient.
一名患有精神疾病的24岁女性发生了致命的播散性人疱疹病毒2型感染。病毒进入的主要部位似乎是上呼吸道，尽管宫颈和肛门也可能是原发部位。类固醇治疗促进了感染的播散。气管内插管可能增加了向下呼吸道的传播，而宫内节育器可能有助于向子宫的传播。呼吸道分泌物中含有核内包涵体的细胞应提醒临床医生，即使在非免疫功能低下的患者中，也可能存在局部和播散性疱疹病毒疾病。
