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儿童躯体感觉脊髓和皮层诱发电位的比较研究(作者译)

[Comparative investigation of somatosensory spinal and cortical evoked potentials in children (author's transl)].

作者信息

Sauer M, Schenck E

出版信息

Arch Psychiatr Nervenkr (1970). 1977 Jul 15;223(4):295-308. doi: 10.1007/BF00346507.

Abstract

Somatosensory spinal (spinEP) and primary cortical evoked responses (ssEP) to median and tibial nerve stimulation (at forefinger, wrist, and ankle respectively) were investigated by means of summation techniques in 23 normal children aged 6 to 14 years. Amplitude recovery functions of cervical spinEP were tested by paired stimuli and short tetanic stimulation at the wrist; spinEP amplitudes were unchanged for stimulus intervals down to 5 ms. The amplitudes of the cervical spinEP after strong stimuli to the finger were only a quarter as great as those obtained by stimulation of the wrist at motor threshold strength. In one patient with the Brown-Séquard syndrome cervical spinEP were absent for stimuli on the side of position sense impairment, but were unaffected for stimuli on the side of dissociated sensory loss. The normal latencies of spinEP (to the onset of the negative potential) and ssEP (to first negative peak) are presented as functions of body height. The difference between these two latencies yielded a central latency from the lower cervical spinal cord of about 9--10 ms. The spinal afferent conduction velocity, calculated from the difference between the lumbar and cervical latencies after tibial nerve stimulation at the ankle, was found to be 74m/s.

摘要

采用叠加技术,对23名6至14岁的正常儿童进行了研究,以观察正中神经和胫神经刺激(分别在前指、腕部和踝部)时的体感脊髓诱发电位(spinEP)和初级皮层诱发电位(ssEP)。通过在腕部进行成对刺激和短强直刺激来测试颈段spinEP的波幅恢复功能;对于刺激间隔低至5毫秒的情况,spinEP波幅未发生变化。在运动阈强度下,对指部进行强刺激后,颈段spinEP的波幅仅为刺激腕部所获波幅的四分之一。在一名患有布朗 - 色夸综合征的患者中,在位置觉受损侧进行刺激时,颈段spinEP消失,但在感觉分离性缺失侧进行刺激时,其不受影响。spinEP(至负电位起始)和ssEP(至首个负峰)的正常潜伏期以身高的函数形式呈现。这两个潜伏期之间的差异得出了来自下颈段脊髓的中枢潜伏期约为9 - 10毫秒。通过计算踝部胫神经刺激后腰段和颈段潜伏期之间的差异,发现脊髓传入神经传导速度为74米/秒。

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