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[马动脉炎病毒:临床症状与预防]

[Equine arteritis virus: clinical symptoms and prevention].

作者信息

Glaser A L, de Vries A A, Rottier P J, Horzinek M C, Colenbrander B

机构信息

Universiteit Utrecht, Faculteit der Diergeneeskunde, Vakgroep Infectieziekten en Immunologie.

出版信息

Tijdschr Diergeneeskd. 1997 Jan 1;122(1):2-7.

PMID:9012008
Abstract

Sero-epidemiological surveys have revealed that equine arteritis virus (EAV) is prevalent in most European countries. The virus causes sporadic cases of respiratory disease and abortion in horses, the incidence of which has increased in recent years. Mares and geldings eliminate virus after acute infection, but 30% to 60% of stallions become persistently infected. In these animals, EAV is maintained within the reproductive tract and is shed continuously in the semen. Persistent infection with EAV in stallions has no negative consequences for fertility but mares inseminated with virus-contaminated semen can have an acute infection. These mares shed large amounts of virus in respiratory secretions and urine, leading to lateral spread of the virus to other susceptible horses. Acute infection at later stages of gestation can lead to abortion. Effective control of the spread of EAV infection depends on the identification of virus-shedding stallions. Persistently infected stallions should not be used for breeding or should be bred only to seropositive mares. Mares bred to shedding stallions should be isolated from other animals for a period of 3 weeks following insemination to prevent the lateral spread of EAV.

摘要

血清流行病学调查显示,马动脉炎病毒(EAV)在大多数欧洲国家普遍存在。该病毒可引发马的散发性呼吸道疾病和流产病例,近年来其发病率有所上升。母马和去势雄马在急性感染后会清除病毒,但30%至60%的种马会持续感染。在这些动物中,EAV在生殖道内持续存在,并通过精液持续排出。种马持续感染EAV对生育能力没有负面影响,但用受病毒污染的精液授精的母马可能会发生急性感染。这些母马会在呼吸道分泌物和尿液中大量排出病毒,导致病毒横向传播给其他易感马匹。妊娠后期的急性感染可导致流产。有效控制EAV感染的传播取决于识别出排毒种马。持续感染的种马不应用于繁殖,或仅应与血清学阳性的母马交配。与排毒种马交配的母马在授精后应与其他动物隔离3周,以防止EAV的横向传播。

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