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腹部手术期间对流加温对术后早期热平衡的影响

[The effect of convection warming during abdominal surgery on the early postoperative heat balance].

作者信息

Kaudasch G, Schempp P, Skierski P, Turner E

机构信息

Klinik für Anästhesiologie und Operative Intensivmedizin, Reinhard-Nieter-Krankenhaus Wilhelmshaven.

出版信息

Anaesthesist. 1996 Nov;45(11):1075-81. doi: 10.1007/s001010050342.

Abstract

UNLABELLED

Hypothermia (core temperature < 36 degrees C) is common after longer-lasting surgical procedures. Heat loss mainly occurs during anaesthesia and surgery and leads to increased risk, especially in the early recovery period of elderly patients. In the present study we investigated the effects of intraoperative forced-air warming, administered via an upper-body blanket ("Warm Touch", Mallinckrodt, USA), with the specific aims of: (1) drawing up heat balances; and (2) analysing postoperative thermoregulation, oxygen consumption (VO2) and cardiovascular reactions of mechanically ventilated patients. The general aim of our study was to compare intraoperative forced-air-warming and conventional patient-insulation with cotton blankets.

METHODS

Twenty four ASA II and III patients scheduled for elective colon surgery were randomly assigned to a control group (n = 12, no warming therapy, upper body covered with a cotton hospital blanket) or a convective warming group (n = 12). Anaesthesia was administered with etomidate (0.2 mg/kg), fentanyl (approximately 10 micrograms/kg) and vecuronium bromide (0.1 mg/kg). During surgery the lungs were mechanically ventilated with 70% nitrous oxide in oxygen and enflurane (end-tidal-concentration max. 0.7%) using a semiclosed circuit with a fresh gas flow of 3 l/min. A hygrophobe heat and moisture exchanger ("Sterivent," Darex Corp., Italy) was used. At the end of surgery patients were transferred to the ICU, covered with a hospital cotton-quilt and normo-ventilated using a Bennett 7200 a. Patients were sedated/kept free of pain by administering titrated doses of midazolam and/or piritramide. Postoperative oxygen consumption (VO2) was recorded continuously with a Deltatrac Metabolic Monitor (Datex Corp., Finland). Pre-, intra- and postoperative measurements included heart rate, invasive blood pressure, core-temperature (before and after operation: urinary bladder-temperature, during surgery: oesophageal temperature) and mean-skin-temperature (according to Ramanathan) up to 180 min from the end of surgery. Shivering, pharmacological interventions (e.g. pethidine) and time of extubation were noted. Data are presented as median, minima and maxima. The results were analysed using the Mann-Whitney U test or Chi-Square test (shivering). Statistical significance was assumed when P < 0.05.

RESULTS

Both groups were comparable for gender, body weight, height, age, duration of their operations and amount of intraoperative fluids, narcotics and muscle relaxants. Room temperatures in the control group were significantly higher than in the forced air group (24 vs 22 degrees C). Initial setting of the forced-air blower was "high" (42-46 degrees high air flow). When the oesophageal-temperature reached 36.5 degrees C, the blower temperature was reduced to 36-40 degrees C. Reduction was necessary approximately 60 min from start in the operation. At the end of surgery/administration to the ICU core-temperatures of both groups differed significantly (35.2/ 35.4 degrees C vs 36.3/36.2 degrees C). Mean-skin temperatures were higher, too, but no statistical analysis was carried out for the intraoperative period, because warm air influenced skin thermometers located on the upper body. At admission to the ICU patients in the control group had a heat loss of 4.4 kJ/kg; those in the convective warming group had a heat-gain of 0.8 kJ/kg. Further measurements of postoperative core temperatures did not differ significantly, but the skin-temperatures of patients who received forced-air warming in the theatre remained higher (P < 0.05) until 120 min from the end of surgery. Shivering was more frequent and lasted longer in the control group (8 patients, 20 min vs 4 patients, 9 min; P < 0.05). Patients in the control group needed more drugs to stop increased cardiovascular reactions (hypertension, tachycardia) or shivering.(ABSTRACT TRUNCATED)

摘要

未标注

体温过低(核心温度<36摄氏度)在较长时间的外科手术之后很常见。热量散失主要发生在麻醉和手术期间,并导致风险增加,尤其是在老年患者的早期恢复阶段。在本研究中,我们调查了通过上身毯子(“Warm Touch”,美国马利克罗斯特公司)进行术中强制空气加温的效果,具体目的是:(1)绘制热量平衡图;(2)分析机械通气患者术后的体温调节、耗氧量(VO2)和心血管反应。我们研究的总体目的是比较术中强制空气加温和用棉被进行的传统患者保暖措施。

方法

24例计划进行择期结肠手术的ASA II级和III级患者被随机分为对照组(n = 12,不进行加温治疗,上身覆盖医院棉被)或对流加温组(n = 12)。使用依托咪酯(0.2 mg/kg)、芬太尼(约10微克/千克)和维库溴铵(0.1 mg/kg)进行麻醉。手术期间,使用半封闭回路,以3升/分钟的新鲜气流,用70%氧化亚氮和氧气以及安氟醚(呼气末浓度最大0.7%)对肺部进行机械通气。使用了一种疏水型热湿交换器(“Sterivent”,意大利达rex公司)。手术结束时患者被转入重症监护病房(ICU),盖上医院棉被,并用贝内特7200 a进行正常通气。通过给予滴定剂量的咪达唑仑和/或匹利卡明使患者镇静/止痛。使用德尔塔拉克代谢监测仪(芬兰Datex公司)连续记录术后耗氧量(VO2)。术前、术中和术后的测量包括心率、有创血压、核心温度(手术前和手术后:膀胱温度,手术期间:食管温度)以及直至手术结束后180分钟的平均皮肤温度(根据拉马纳坦法)。记录寒战、药物干预(如哌替啶)和拔管时间。数据以中位数、最小值和最大值表示。结果采用曼-惠特尼U检验或卡方检验(寒战)进行分析。当P<0.05时认为具有统计学意义。

结果

两组在性别、体重、身高、年龄、手术持续时间以及术中液体、麻醉药和肌肉松弛剂用量方面具有可比性。对照组的室温显著高于强制空气组(24摄氏度对22摄氏度)。强制空气吹风机的初始设置为“高”(42 - 46摄氏度高气流)。当食管温度达到36.5摄氏度时,吹风机温度降至36 - 40摄氏度。大约在手术开始后60分钟需要进行温度降低。手术结束/转入ICU时,两组的核心温度有显著差异(35.2/35.4摄氏度对36.3/36.2摄氏度)。平均皮肤温度也较高,但术中未进行统计分析,因为暖空气影响了位于上身的皮肤温度计。转入ICU时,对照组患者有4.4千焦/千克的热量散失;对流加温组患者有0.8千焦/千克的热量增加。术后核心温度的进一步测量无显著差异,但在手术室接受强制空气加温的患者的皮肤温度在手术结束后120分钟内仍较高(P<0.05)。对照组寒战更频繁且持续时间更长(8例患者,20分钟对4例患者,9分钟;P<0.05)。对照组患者需要更多药物来抑制增加的心血管反应(高血压、心动过速)或寒战。(摘要截断)

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