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[肾动脉纤维肌发育不良]

[Fibromuscular dysplasia of the renal arteries].

作者信息

Golosovskaia M A, Spiridonov A A, Cherkasov A P

出版信息

Arkh Patol. 1977;39(5):19-25.

PMID:901251
Abstract

Thirty-two cases of fibrous-muscular dysplasial of renal arteries (including one autopsy case) were studied. Sections of renal arteries removed at reconstructive operations from patients suffering from renovascular hypertension were examined. Two morphological variants of the process were distinguished: medial dysplasia (perimedial fibroplasia, medial fibroplasia, and dissecting aneurysm) and intimal proliferation. Morphologically, fibrous-muscular dysplasia is a manifestation of proliferation of smooth muscle cell which appears to have various forms and stages. Diagnostically, fibrous-muscular dysplasia should be differentiated from atherosclerosis, nonspecific arteritis, proliferation of the intima due to hypovolemia, and perivascular sclerosis of different etiologies.

摘要

对32例肾动脉纤维肌发育不良患者(包括1例尸检病例)进行了研究。对因肾血管性高血压接受重建手术的患者切除的肾动脉切片进行了检查。区分出该病变的两种形态学变异:中膜发育不良(周中膜纤维增生、中膜纤维增生和夹层动脉瘤)和内膜增生。从形态学上看,纤维肌发育不良是平滑肌细胞增殖的一种表现,似乎有多种形式和阶段。在诊断上,纤维肌发育不良应与动脉粥样硬化、非特异性动脉炎、低血容量引起的内膜增生以及不同病因的血管周围硬化相鉴别。

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