van den Hoed R D, Feldberg M A, van Leeuwen M S, van Dalen T, Obertop H, Kooyman C D, van der Schouw Y T, de Graaf P W
Center of Radiology, Utrecht University Hospital, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands.
Abdom Imaging. 1997 Mar-Apr;22(2):132-7. doi: 10.1007/s002619900157.
To improve computed tomographic (CT) prediction of local irresectability and to correlate preoperative CT findings with patient outcome.
Eighty-five patients with esophageal carcinoma underwent CT in supine, left lateral decubitus, and prone positions. CT signs that were indicative of local irresectability included (1) an angle of contact >45 degrees with the aorta; (2) obliteration of triangular fat pad between the tumor, aorta, and spine; (3) tumor contiguous with the aorta in all three positions; and (4) indentation of the airway in all three positions.
All CT signs indicative for local irresectability concerning the aorta had comparable percentages of false-positive scans (75%) when correlated with surgical findings. When correlated with pathologic findings, >45 degrees angle of contact with the aorta yielded the fewest false-positive cases (9%). Concerning the airway, additional positions changed the staging correctly in 1 of 18 cases. Median survival was 21 and 8 months, respectively, for tumors considered CT resectable or irresectable.
Additional patient positions do not improve the CT prediction of aortic invasion. Predicted resectability correlates with a significant longer life expectancy.
为改善计算机断层扫描(CT)对局部不可切除性的预测,并将术前CT表现与患者预后相关联。
85例食管癌患者分别在仰卧位、左侧卧位和俯卧位接受CT检查。提示局部不可切除的CT征象包括:(1)与主动脉的接触角>45度;(2)肿瘤、主动脉和脊柱之间的三角形脂肪垫消失;(3)在所有三个体位下肿瘤均与主动脉相邻;(4)在所有三个体位下气道受压。
与手术结果相关时,所有提示主动脉局部不可切除的CT征象假阳性扫描百分比相当(75%)。与病理结果相关时,与主动脉接触角>45度的假阳性病例最少(9%)。关于气道,在18例中有1例通过额外体位正确改变了分期。CT检查认为可切除或不可切除的肿瘤患者中位生存期分别为21个月和8个月。
增加患者体位并不能改善CT对主动脉侵犯的预测。预测的可切除性与显著更长的预期寿命相关。