Selwyn M J, Walker H A
Biochem J. 1977 Jul 15;166(1):137-9. doi: 10.1042/bj1660137.
Osmotic-swelling techniques show that HCO3- enters mitochondria by an electrogenic process, effectively HCO3- uniport, under non-energized conditions. This mode of translocation accounts for previous reports of non-entry of HCO3- in experiments with energy-linked Ca2+ uptake. The effects of HCO3- on mitochondrial respiration are reported and discussed.
渗透膨胀技术表明,在非能量化条件下,HCO₃⁻通过一种生电过程进入线粒体,实际上是HCO₃⁻单向转运。这种转运模式解释了先前在能量偶联的Ca²⁺摄取实验中关于HCO₃⁻不进入的报道。本文报道并讨论了HCO₃⁻对线粒体呼吸的影响。