Okura M, Tomotake M, Mori K, Ikuta T
Department of Neuropsychiatry, University of Tokushima School of Medicine, Japan.
Psychiatry Clin Neurosci. 1996 Dec;50(6):317-21. doi: 10.1111/j.1440-1819.1996.tb00572.x.
We described the case of a 59 year old female with transient global amnesia (TGA) who had been examined neuropsychologically using Sternberg's paradigm and a random number generation (RNG) task on the following day, 1 week and 4 weeks after a TGA episode. The slope value of the linear function, a measure of cognitive memory scanning speed, decreased with time and showed a marked decrease 1 week after TGA, suggesting that the stage of serial and exhaustive scanning recovered within 1 week. The zero-intercept value, on the other hand, increased during 1 week but decreased 4 weeks later and was not related directly to recovery from TGA. The performance in RNG task improved 1 week later, but deteriorated 4 weeks after the episode. Such a change in RNG was in accordance with that of the zero-intercept value, predicting a relationship. It is concluded that the subclinical memory deficit, detected with these tasks, persisted longer than clinical recovery from TGA.
我们描述了一例59岁患有短暂性全面性遗忘症(TGA)的女性病例。在TGA发作后的次日、1周和4周,对其进行了神经心理学检查,采用了斯特恩伯格范式和随机数字生成(RNG)任务。线性函数的斜率值是认知记忆扫描速度的一种度量,它随时间下降,在TGA发作1周后显著下降,这表明串行和穷举扫描阶段在1周内恢复。另一方面,零截距值在1周内增加,但在4周后下降,且与TGA的恢复没有直接关系。RNG任务的表现在1周后有所改善,但在发作4周后恶化。RNG的这种变化与零截距值的变化一致,预示着两者之间存在关联。得出的结论是,通过这些任务检测到的亚临床记忆缺陷比TGA的临床恢复持续时间更长。