Yamada K, Kanba S, Murata T, Fukuzawa M, Terashi B, Yagi G, Asai M
Department of Neuropsychiatry, Keio University, School of Medicine, Tokyo, Japan.
Psychiatry Clin Neurosci. 1996 Dec;50(6):341-2. doi: 10.1111/j.1440-1819.1996.tb00578.x.
We investigated the efficacy of Shakuyaku-kanzo-to (TJ-68) in neuroleptic-induced hyperprolactinemia in 11 treated schizophrenic patients. The mean plasma prolactin level decreased significantly from 28.9 +/- 14.5 ng/mL at baseline to 22.0 +/- 15.2 ng/mL at 4 weeks. Potassium levels did not change significantly. Neither the exacerbation of psychosis nor other adverse effects occurred.
我们对11例接受治疗的精神分裂症患者,研究了芍药甘草汤(TJ - 68)治疗抗精神病药物所致高催乳素血症的疗效。血浆催乳素平均水平从基线时的28.9±14.5 ng/mL显著降至4周时的22.0±15.2 ng/mL。血钾水平无显著变化。未出现精神病症状加重或其他不良反应。