Haunerland N H
Department of Biological Sciences, Simon Fraser University, Burnaby, B.C., Canada.
Insect Biochem Mol Biol. 1996 Sep-Oct;26(8-9):755-65. doi: 10.1016/s0965-1748(96)00035-5.
The accumulation and utilization of storage proteins are prominent events linked to the metamorphosis of holometabolous insects. Storage proteins are synthesized in fat body, secreted into the larval hemolymph and taken up by fat body shortly before pupation. Within the pupal fat body, these proteins are initially stored in protein granules, and later proteolytically broken down to supply amino acid resources necessary for the completion of adult development. Most, but not all storage proteins belong to a superfamily of hexameric larval serum proteins that are evolutionarily related to hemocyanin. This article reviews the classification of these proteins, based on their amino acid sequences, and the current knowledge of the receptors that mediate their selective uptake into pupal fat body.
储存蛋白的积累和利用是与全变态昆虫变态相关的突出事件。储存蛋白在脂肪体中合成，分泌到幼虫血淋巴中，并在化蛹前不久被脂肪体摄取。在蛹期脂肪体中，这些蛋白最初储存在蛋白颗粒中，随后通过蛋白水解作用分解，以提供成虫发育完成所需的氨基酸资源。大多数（但并非全部）储存蛋白属于六聚体幼虫血清蛋白超家族，它们在进化上与血蓝蛋白相关。本文基于这些蛋白的氨基酸序列对其分类进行了综述，并介绍了介导其选择性摄取到蛹期脂肪体中的受体的当前知识。
