Roy A, Biswas S, Singh N
Malaria Research Centre, Delhi, India.
Indian J Malariol. 1996 Sep;33(3):144-53.
A recently developed peptide ELISA method was used for monitoring the efficacy of malaria control programme in the tribal areas of Madhya Pradesh. Both crude Pf antigen and synthetic nonapeptide were used in ELISA for seroepidemiological studies. Both antigen responded equally well but the synthetic peptide had advantages of purity, defined characteristic and easy availability. Population of Mandla protected by vector control measures showed lower antibody titre and lower percentage positivity compared to the unprotected population of Jabalpur. A 0-5 yrs sentinel population from Haldwani almost seronegative has been taken as control.
一种最近开发的肽酶联免疫吸附测定（ELISA）方法被用于监测中央邦部落地区疟疾控制项目的效果。在血清流行病学研究的ELISA中使用了粗制疟原虫抗原和合成九肽。两种抗原的反应效果相同，但合成肽具有纯度高、特性明确和易于获取的优点。与贾巴尔普尔未受保护的人群相比，通过病媒控制措施得到保护的曼德拉人群显示出较低的抗体滴度和较低的阳性率。来自哈德瓦尼的0至5岁几乎血清阴性的哨点人群被用作对照。
