Byrd R W, Byrd R P, Roy T M
J Ky Med Assoc. 1997 Jan;95(1):19-22.
The potential difficulties offered by the presence of a solitary pulmonary nodule in a patient with rheumatoid arthritis are illustrated by a male non-smoker with clinical, serologic and radiographic rheumatoid arthritis, active and fibrosing alveolitis and a new lung nodule. This nodule proved to be squamous cell carcinoma without the typical risk factors. The findings of a solitary pulmonary density or nodule in a patient with rheumatoid arthritis provides no assurance that the lesion is benign. Both necrobiotic nodules and lung cancer may present as solitary pulmonary nodules in patients with this autoimmune disease.
一名不吸烟男性患者，患有临床、血清学及影像学表现的类风湿关节炎、活动性和纤维化肺泡炎且出现了新的肺结节，这说明了类风湿关节炎患者出现孤立性肺结节可能带来的潜在困难。该结节被证实为鳞状细胞癌，却没有典型的风险因素。类风湿关节炎患者出现孤立性肺密度影或结节，并不能保证该病变是良性的。在这种自身免疫性疾病患者中，坏死性结节和肺癌都可能表现为孤立性肺结节。
