Patil M S, Kaklij G S, Poduval T B, Singh B B
Radiation Biology and Biochemistry Division, Bhabha Atomic Research Centre, Bombay, India.
Indian J Exp Biol. 1996 Sep;34(9):842-4.
The whole-body hyperthermia (40 degrees C, 1 hr) 20-48 hr prior to total-body irradiation (TBI) with 9 Gy gamma rays gave 80% protection as assessed by survival of the animals. However this was reduced to 50% when mice were irradiated 7 or 15 days after hyperthermia. The local hyperthermia (42 degrees C, 1 hr) given prior to irradiation, on the other hand, did not show any protective effect. The whole-body or local hyperthermia given after TBI had no protective effect on survival of animals.
在全身照射(TBI)9 Gy γ射线前20 - 48小时进行全身热疗(40摄氏度,1小时),根据动物存活率评估,可提供80%的保护作用。然而,当小鼠在热疗后7天或15天接受照射时,这种保护作用降至50%。另一方面,在照射前进行局部热疗(42摄氏度,1小时)未显示出任何保护作用。在TBI后进行全身或局部热疗对动物存活率没有保护作用。