Dromerick A W, Meschia J F, Kumar A, Hanlon R E
Stroke Rehabilitation Service, Division of Rehabilitation, Washington University School of Medicine, St. Louis, MO, USA.
Arch Phys Med Rehabil. 1997 Jan;78(1):92-4. doi: 10.1016/s0003-9993(97)90018-6.
A patient suffered the onset of simultaneous bilateral thalamic hemorrhage several hours after the administration of intravenous tissue plasminogen activator. The patient exhibited features of the paramedian diencephalic syndrome, including executive dysfunction, anterograde amnesia, inattention, and disturbances of visual perception. During rehabilitation, she made significant gains in overlearned activities of daily living tasks, but her inability to retain new information left her severely disabled. The use of intravenous thrombolytic therapy is believed to account for this patient's unusual stroke syndrome. With recent evidence supporting the efficacy of intravenous thrombolysis in acute stroke, patients with multiple hemorrhagic strokes as a result of thrombolysis may become more common on rehabilitation services.
一名患者在静脉注射组织纤溶酶原激活剂数小时后出现双侧丘脑同时出血。该患者表现出中脑间脑综合征的特征，包括执行功能障碍、顺行性遗忘、注意力不集中和视觉感知障碍。在康复过程中，她在过度学习的日常生活任务方面取得了显著进展，但由于无法记住新信息，她仍然严重残疾。静脉溶栓治疗被认为是导致该患者出现不寻常中风综合征的原因。随着最近有证据支持静脉溶栓治疗在急性中风中的疗效，因溶栓导致多发性出血性中风的患者在康复服务中可能会变得更加常见。
