Lipton R B
University of Illinois, School of Public Health, Division of Epidemiology and Biostatistics, Chicago 60612, USA.
Diabetes Res Clin Pract. 1996 Oct;34 Suppl:S173-9. doi: 10.1016/s0168-8227(96)90026-1.
Little information is available about insulin-dependent diabetes mellitus (IDDM) when it occurs among US minorities. The incidence of IDDM among African-American and Hispanic children < 18 years of age was determined in the city of Chicago. Hospital records were used as the primary source of cases, and a small amount of additional data was collected from the medical charts. Cases were drawn from records at 37 hospitals in Cook County, IL. African-American and Hispanic patients using insulin, residing in the city of Chicago, and < 18-years-old at onset were registered. Three secondary sources were used and overall ascertainment was estimated at 86%. There were 413 new cases during the 6-year interval 1985 through 1990. The age-standardized incidence of IDDM was 13.2/100,000 (95% confidence interval (C.I.) 11.8-14.8) among African-Americans and 10.8/100,000 (95% C.I. 9.5-12.3) among Hispanics. Hospital use differed between African-Americans and Hispanics, presumably based on geographic, cultural and financial factors. Diabetes among the first degree relatives of children from both ethnic groups was common, and the most frequently listed co-morbid conditions were asthma and obesity. The risk for IDDM in Chicago is among the highest for both African-origin and Hispanic children worldwide. The prevalence of asthma and obesity parallels the high prevalence of these conditions among non-diabetic children in Chicago. The ongoing epidemic of non-insulin-dependent diabetes mellitus (NIDDM) among African-Americans and US Hispanics is likely to be the reason for the large number of minority IDDM patients who have a first-degree relative with diabetes.
关于胰岛素依赖型糖尿病(IDDM)在美国少数族裔中发病的信息很少。在芝加哥市确定了18岁以下非裔美国人和西班牙裔儿童中IDDM的发病率。医院记录用作病例的主要来源,并从病历中收集了少量额外数据。病例取自伊利诺伊州库克县37家医院的记录。登记了居住在芝加哥市、发病时年龄小于18岁且使用胰岛素的非裔美国人和西班牙裔患者。使用了三个二级来源,总体确诊率估计为86%。在1985年至1990年的6年期间有413例新病例。非裔美国人中IDDM的年龄标准化发病率为13.2/100,000(95%置信区间(C.I.)11.8 - 14.8),西班牙裔为10.8/100,000(95% C.I. 9.5 - 12.3)。非裔美国人和西班牙裔之间的医院使用情况不同,可能基于地理、文化和经济因素。两个族裔儿童的一级亲属中糖尿病很常见,最常列出的合并症是哮喘和肥胖。在全球范围内,芝加哥非裔和西班牙裔儿童患IDDM的风险是最高的之一。哮喘和肥胖的患病率与芝加哥非糖尿病儿童中这些疾病的高患病率相似。非裔美国人和美国西班牙裔中正在流行的非胰岛素依赖型糖尿病(NIDDM)可能是大量有糖尿病一级亲属的少数族裔IDDM患者的原因。