Barnard M L, Schwieso J E, Thomas E L, Bell J D, Saeed N, Frost G, Bloom S R, Hajnal J V
Robert Steiner MR Unit, Hammersmith Hospital, Royal Postgraduate Medical School, London, UK.
NMR Biomed. 1996 Jun;9(4):156-64. doi: 10.1002/(SICI)1099-1492(199606)9:4<156::AID-NBM412>3.0.CO;2-B.
Fast scan magnetic resonance imaging techniques for adipose tissue (AT) quantification were compared to a conventional T1-weighted spin-echo (SE) sequence (TR = 500 ms, TE = 20 ms), imaging a mid-abdominal slice. A rapid T1-weighted SE sequence (TR = 36 ms, TE = 14 ms) was optimal, with minimal distortion (field, motion, flow artefact). Tissue contrast was higher and visceral AT was clearly differentiated. Quantification of all AT compartments (total, subcutaneous, internal, visceral) showed close agreement with the T1-weighted SE sequence and reproducibility was high (coefficient of variation < 4.7%). For AT quantification in a whole subject, this fast technique allows each image to be acquired serially at the magnet isocenter, as the subject is moved through the scanner (serial isocenter scanning, SIS). This method provides minimal image distortion and allows rapid coverage of the whole body.
将用于脂肪组织（AT）定量的快速扫描磁共振成像技术与传统的T1加权自旋回波（SE）序列（TR = 500 ms，TE = 20 ms）进行比较，对腹部中部切片进行成像。快速T1加权SE序列（TR = 36 ms，TE = 14 ms）是最佳的，具有最小的失真（场、运动、流动伪影）。组织对比度更高，内脏脂肪组织清晰可辨。所有脂肪组织区域（总、皮下、内部、内脏）的定量结果与T1加权SE序列显示出高度一致性，并且重复性很高（变异系数<4.7%）。对于整个受试者的脂肪组织定量，这种快速技术允许在受试者通过扫描仪移动时，在磁体等中心连续采集每个图像（连续等中心扫描，SIS）。该方法提供最小的图像失真，并允许快速覆盖全身。
