Alexander W D, Polak A
Br Heart J. 1977 Aug;39(8):900-2. doi: 10.1136/hrt.39.8.900.
An early diastolic murmur thought to indicate functional aortic regurgitation was heard in 7 of 74 consecutive patients with end-stage renal failure assessed for chronic intermittent haemodialysis and transplantation. In all 7 cases the murmur was transient and related to episodes of hypertension and fluid overload and disappeared on correction of these factors. In a further 2 patients aortic regurgitation resulted from a structural abnormality of the aortic valve. Thus, an early diastolic murmur is not uncommon in this situation and does not necessarily indicate organic aortic valve disease which might preclude selection for haemodialysis and transplantation.
在74例接受慢性间歇性血液透析和移植评估的终末期肾衰竭患者中，连续7例患者听到舒张早期杂音，该杂音被认为提示功能性主动脉瓣关闭不全。在所有7例患者中，杂音均为一过性，与高血压和液体超负荷发作有关，在这些因素得到纠正后杂音消失。另外2例患者的主动脉瓣关闭不全是由主动脉瓣结构异常所致。因此，在这种情况下，舒张早期杂音并不少见，也不一定提示器质性主动脉瓣疾病，后者可能会妨碍患者被选作血液透析和移植对象。
