系统性红斑狼疮伴膜性肾小球肾炎和子宫血管炎。

Systemic lupus erythematosus with membranous glomerulonephritis and uterine vasculitis.

作者信息

Feriozzi S, Muda A O, Amini M, Faraggiana T, Ancarani E

机构信息

Divisione di Nefrologia e Dialisi e Anatomia ed Istologia Patologica, Ospedale Grande degli Infermi, Azienda USL/Vt, Viterbo, Italy.

出版信息

Am J Kidney Dis. 1997 Feb;29(2):277-9. doi: 10.1016/s0272-6386(97)90041-x.

DOI:10.1016/s0272-6386(97)90041-x

PMID:9016901

Abstract

We report a case of lupus vasculitis with uterine localization and concurrent membranous nephropathy. Immunofluorescence study suggested the occurrence of an immune complex nephropathy and a pauci-immune pathogenesis of vasculitis. Our case points out the event of tissue damage in two organs mediated by different pathogenetic mechanisms. In addition, uterine vasculitis without pregnancy may be observed in patients with systemic lupus erythematosus nephritis.

摘要

我们报告一例狼疮性血管炎累及子宫并并发膜性肾病的病例。免疫荧光研究提示存在免疫复合物性肾病以及血管炎的寡免疫发病机制。我们的病例指出了由不同致病机制介导的两个器官的组织损伤情况。此外，系统性红斑狼疮肾炎患者可能出现非妊娠状态下的子宫血管炎。