Plasma, bone, hip capsule, synovial and drain fluid concentrations of lincomycin during total hip replacement.
作者信息
Parsons R L, Beavis J P, Hossack G A, Paddock G M
出版信息
Br J Clin Pharmacol. 1977 Aug;4(4):433-7. doi: 10.1111/j.1365-2125.1977.tb00758.x.
Abstract
1 Lincomycin (600 mg) was given 6 h preoperatively by intramuscular injection, as an intravenous infusion over 30 min and for 72 h postoperatively in twelve patients having total hip replacement. 2 The plasma, bone, hip capsule, synovial and drain fluid concentrations of lincomycin were almost always above the M.I.C. of lincomycin against penicillinase producing Staphylococcus aureus. 3 There was a good correlation between the estimated concentrations of lincomycin in bone by the grinding and agitation methods of analysis. 4 Two patients developed pseudomembranous colitis after parenteral lincomycin.
摘要
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引用本文的文献
1
Plasma, bone, hip capsule and drain fluid concentrations of ampicillin and flucloxacillin during total hip replacement after intravenous bolus injection of magnapen.
Br J Clin Pharmacol. 1978 Aug;6(2):135-43. doi: 10.1111/j.1365-2125.1978.tb00838.x.
2
Plasma concentration/time curve of erythromycin after a 12-hour intravenous infusion of erythromycin lactobionate in man.
Postgrad Med J. 1978 Feb;54(628):68-71. doi: 10.1136/pgmj.54.628.68.
本文引用的文献
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