Gurkoveskaia A V, Buryĭ V A
Biofizika. 1977 Jul-Aug;22(4):676-9.
The electrical and contractile responses of smooth muscle cells of the rabbit a. pulmonalis and pigeon a. carotis were investigated using extracellular stimulation through sucrose gap and intracellular recording of electrotonic potentials at different distances from the sucrose partitition. Neither spontaneous nor evoked electrical and contractile activities were registered in normal Krebs solution. Current-voltage relations of these muscle cells showed marked rectification. The amplitude of anelectrotonic potentials decreased exponentially with the distance from sucrose partitition, while the time to reach the half-amplitude of the electrotonic potentials was linear function of the distance. These facts indicate that cable equations can be applied to these muscles. The space constant calculated for the rabbit a. pulmonalis was equal to 1.2 mm and that for the pigeon a. carotis--to 1.0 mm. Results of these experiments strongly suggest the existence of low resistance pathways between arterial muscle cells.
利用蔗糖间隙进行细胞外刺激，并在距蔗糖分隔不同距离处对电紧张电位进行细胞内记录，研究了家兔肺动脉和家鸽颈动脉平滑肌细胞的电反应和收缩反应。在正常的克雷布斯溶液中，未记录到自发的或诱发的电活动和收缩活动。这些肌肉细胞的电流-电压关系表现出明显的整流特性。电紧张电位的幅度随距蔗糖分隔的距离呈指数下降，而达到电紧张电位半幅度的时间是距离的线性函数。这些事实表明电缆方程可应用于这些肌肉。计算出家兔肺动脉的空间常数为1.2毫米，家鸽颈动脉的空间常数为1.0毫米。这些实验结果有力地表明动脉肌细胞之间存在低电阻通路。
