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Flow cytometric evaluation of non anti-RH1(D) monoclonal Rh antibodies.

作者信息

Le Pennec P Y, Gane P, Noizat-Pirenne F, Braddock D, Cartron J P, Rouger P

机构信息

Centre National de Référence pour les Groupes Sanguins, Institut National de la Transfusion Sanguine, Paris, France.

出版信息

Transfus Clin Biol. 1996;3(6):433-5. doi: 10.1016/s1246-7820(96)80059-0.

DOI:10.1016/s1246-7820(96)80059-0
PMID:9018804
Abstract

IgG non anti-RH1(D) monoclonal Rh antibodies were evaluated by flow cytometry. The values obtained with these antibodies were less strong than those obtained with anti-RH1(D) antibodies. For a significant number of antibodies, the signal was not high enough to give reliable results for the antibody specificity. Despite these drawbacks, flow cytometry was an efficient tool to appreciate the variation of reactivity by different antibodies with normal or variant cells. These variations were not always obvious by serological means.

摘要

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