一项关于无髓神经纤维传导速度的研究。
A study of conduction velocity in nonmyelinated nerve fibers.
作者信息
Matsumoto G, Tasaki I
出版信息
Biophys J. 1977 Oct;20(1):1-13. doi: 10.1016/S0006-3495(77)85532-X.
Abstract
By treating a nonmyelinated nerve fiber as a continuous cable consisting of three distinct zones (Resting, transitional, and excited), the following mathematical expression was derived: (formula: see text) where v is the conduction velocity, d the diameter of the fiber, R the resistance of the membrane of unit area at the peak of excitation, rho the resistivity of the medium inside the fiber, and C the capacity of membrane per unit area. The validity of this expression was demonstrated by using squid giant nerve fibers intracellularly perfused with dilute salt solutions. The relationship between these results and previous theories and experiments on conduction velocity is discussed.
摘要
通过将无髓神经纤维视为由三个不同区域（静息、过渡和兴奋）组成的连续电缆，得出了以下数学表达式：（公式：见正文）其中v是传导速度，d是纤维直径，R是兴奋峰值时单位面积膜的电阻，ρ是纤维内部介质的电阻率，C是单位面积膜的电容。通过使用用稀盐溶液进行细胞内灌注的鱿鱼巨神经纤维，证明了该表达式的有效性。讨论了这些结果与先前关于传导速度的理论和实验之间的关系。
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