Ghosal A G, Mandal T K, Chowdhury T K, Mukherjee K, Mukherjee D
Department of Chest Medicine, Calcutta, National Medical College.
J Indian Med Assoc. 1996 Sep;94(9):328-30.
Susceptibility and/or immune response to tuberculosis may or may not be associated with particular histocompatibility leucocyte antigen (HLA) phenotype frequencies. The present study was undertaken to north eastern Indian population to verify any association between HLA phenotypes and immune response to mycobacterial antigen. HLA-typing was done in 60 well Tarasaki trays and T-cell subsets in each group were measured using Ficoll-hypaque nylon wool columns and dynabeads (M-450). No universal association with particular HLA-type and pulmonary tuberculosis has been confirmed.
对结核病的易感性和/或免疫反应可能与特定的组织相容性白细胞抗原（HLA）表型频率有关，也可能无关。本研究针对印度东北部人群进行，以验证HLA表型与对分枝杆菌抗原的免疫反应之间是否存在关联。在60孔Tarasaki培养板中进行HLA分型，并使用Ficoll-泛影葡胺尼龙棉柱和磁珠（M-450）测量每组中的T细胞亚群。尚未证实特定HLA类型与肺结核之间存在普遍关联。
