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[Immunological studies on cataracts under conditions of exposure to low-dose radiation].

作者信息

Shubik V M, Kvasova M D

机构信息

NII of Radiation Medicine, Saint-Petersburg.

出版信息

Vestn Oftalmol. 1996 Sep-Oct;112(4):21-3.

PMID:9019906
Abstract

Immunopathological changes were studied in cataract patients chronically exposed to low-dose ionizing radiation occupationally or as a result of living in districts polluted with radionuclides after the Chernobyl accident. No cellular autoimmune shifts were detected in the examinees; humoral autoimmune changes in respect of different ocular antigens were revealed. Low-dose ionizing radiation was conducive to the formation of thermostable complement-fixing antibodies to lens tissues. One of the causes of the production of such antibodies were disorders in the helper-suppressor relationships of T-lymphocytes. The studies confirm the hypothesis on the possibility of cataract development as a result of low-dose exposure.

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