Rodríguez Rodríguez R, Burgos Revilla F J, Gómez Dosantos V, Galbis Sanjuan F, Navarro Antolín J, Allona Almagro A, Orofino Azcue L
Servicio de Urología y Nefrología, Hospital Ramón y Cajal, Madrid.
Actas Urol Esp. 1996 Sep;20(8):697-701.
The objective of this paper is to compare the hormonal changes and sexual activity between transplanted patients and patients in regular haemodialysis (HD).
130 patients, 98 RT carriers and 32 with CRF were evaluated with regard to the sexual function. The etiology of CRF is similar in both groups. All patients underwent hormonal determinations (FSH, LH, Prolactin, Testosterone, Oestradiol and PTH), complete serum testing and other diagnostic studies done selectively, 38 of 130 patients (14 in HD and 24 transplants) answered a personal questionnaire on sexual activity.
Oestradiol and prolactin levels are higher in the HD group compared to transplanted patients (p < 0.05). 70% of RT patients maintain their libido versus 35% of those in dialysis (p < 0.01). The former group refers good erection in 55% cases versus 21% of dialysis patients (p < 0.01). Intercourse frequency and degree of overall satisfaction is higher in the RT group (N.S.).
No significant differences were found in FSH, LH and testosterone levels. The normality of FSH levels may be a reflection of the integrity of the germinal line. 65% HD patients refer decreased or absent libido, to which the higher levels of prolactin and oestradiol found could contribute. No relationship was found between sexual function with the type of immunosuppression or the graft function.
本文目的是比较移植患者与常规血液透析（HD）患者的激素变化及性功能。
对130例患者（98例肾移植受者和32例慢性肾衰竭患者）的性功能进行评估。两组慢性肾衰竭的病因相似。所有患者均进行了激素测定（促卵泡激素、促黄体生成素、催乳素、睾酮、雌二醇和甲状旁腺激素）、完整的血清检测以及根据需要进行的其他诊断性检查，130例患者中有38例（血液透析患者14例，移植患者24例）回答了关于性功能的个人问卷。
与移植患者相比，血液透析组的雌二醇和催乳素水平更高（p < 0.05）。70%的肾移植患者保持性欲，而透析患者中这一比例为35%（p < 0.01）。前一组55%的患者勃起功能良好，而透析患者中这一比例为21%（p < 0.01）。肾移植组的性交频率和总体满意度更高（无统计学差异）。
促卵泡激素、促黄体生成素和睾酮水平未发现显著差异。促卵泡激素水平正常可能反映了生殖细胞系的完整性。65%的血液透析患者自述性欲减退或无性欲，这可能与所发现的较高催乳素和雌二醇水平有关。未发现性功能与免疫抑制类型或移植肾功能之间存在关联。
