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禁食-再喂养大鼠胃肠道黏膜中游离脂肪酸和三酰甘油的浓度

Free fatty acids and triacylglycerol concentrations in the gastrointestinal mucosa of fasted-refed rats.

作者信息

Wójcik B M, Namiot Z, Górski J

机构信息

Department of Physiology, Medical Academy of Białystok.

出版信息

Rocz Akad Med Bialymst. 1996;41(2):452-6.

PMID:9020558
Abstract

The aim of the study was to determine the free fatty acids and triacylglycerol concentrations in the gastric, duodenal, ileal and colonic mucosa of fasted-refed rats. As compared to fasted group, refeeding resulted in a significant increase of free fatty acids content in the mucosa of the stomach, ileum, and colon but not in the duodenum, while triacylglycerol concentration increased at that time only in the duodenum; in parallel with the mucosal lipid changes, it was observed a significant decline in plasma free fatty acids level. We suggest that plasma free fatty acids may be implicated in the formation of lipid balance during refeeding in the gastrointestinal mucosa.

摘要

本研究的目的是测定禁食-再喂养大鼠胃、十二指肠、回肠和结肠黏膜中的游离脂肪酸和三酰甘油浓度。与禁食组相比,再喂养导致胃、回肠和结肠黏膜中游离脂肪酸含量显著增加,但十二指肠未增加,而此时三酰甘油浓度仅在十二指肠升高;与黏膜脂质变化同时,观察到血浆游离脂肪酸水平显著下降。我们认为血浆游离脂肪酸可能参与了胃肠道黏膜再喂养期间脂质平衡的形成。

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