Pitzalis M V, Mastropasqua F, Massari F, Passantino A, Forleo C, Luzzi G, Totaro P, De Nicolò M, Rizzon P
Institute of Cardiology, University of Bari, Italy.
Am Heart J. 1997 Feb;133(2):153-61. doi: 10.1016/s0002-8703(97)70203-5.
To identify a method for characterizing the dynamic behavior of ventricular arrhythmias at different heart rates, 201 consecutive patients with frequent premature ventricular contractions (PVCs) underwent two 24-hour electrocardiographic monitoring periods. The percentage of PVCs for each cycle length was calculated and then analyzed by linear regression analysis. On the basis of the significance of the p value, and the positive or negative value of the slope, we identified three trends: a tachycardia-enhanced pattern (p < 0.01, slope negative), a bradycardia-enhanced pattern (p < 0.01, slope positive), and an indifferent pattern (p > 0.01). During the first monitoring period, a tachycardia-enhanced pattern was present in 56 patients (28%), a bradycardia-enhanced pattern was present in 49 patients (24%), and an indifferent pattern was present in 96 patients (48%). This relationship was reproducible in 41 of the patients with a tachycardia-enhanced pattern (73%), in 29 of the patients with a bradycardia-enhanced pattern (59%), and in 70 patients with an indifferent pattern (72%). In conclusion, it is possible to identify a spontaneous trend between the incidence of ventricular arrhythmias and the length of the preceding cardiac cycle that seems to remain stable over time.
为确定一种描述不同心率下室性心律失常动态行为的方法，201例频发室性早搏（PVC）患者接受了两个24小时心电图监测期。计算每个心动周期长度的PVC百分比，然后通过线性回归分析进行分析。根据p值的显著性以及斜率的正负值，我们确定了三种趋势：心动过速增强型（p < 0.01，斜率为负）、心动过缓增强型（p < 0.01，斜率为正）和无差异型（p > 0.01）。在第一个监测期，56例患者（28%）呈现心动过速增强型，49例患者（24%）呈现心动过缓增强型，96例患者（48%）呈现无差异型。这种关系在41例心动过速增强型患者（73%）、29例心动过缓增强型患者（59%）和70例无差异型患者（72%）中具有可重复性。总之，有可能确定室性心律失常发生率与前一心动周期长度之间的自发趋势，且该趋势似乎随时间保持稳定。
