Severe humoral hypercalcemia in primary isolated non-Hodgkin's lymphoma of the heart.
作者信息
Yigla M, Ben-Arieh Y, Beny A, Milo S, Markiewicz W, Reisner S A
机构信息
Division of Pulmonary Diseases, Northern Israel Oncology of Center, Haifa, Israel.
出版信息
Med Pediatr Oncol. 1997 Mar;28(3):183-6. doi: 10.1002/(sici)1096-911x(199703)28:3<183::aid-mpo5>3.0.co;2-f.
Abstract
The etiology of hypercalcemia was investigated in a patient with primary isolated non-Hodgkin's lymphoma of the heart. There was no evidence of bone involvement, and parathyroid hormone and calciterol levels were suppressed. Plasma parathyroid-hormone-related protein (PTHrP 1-86) detected by immunoradiometric assay was increased (15 pmol/l compared with < 0.3 pmol/l in a control). We demonstrated that PTHrP was the humoral mediator of severe hypercalcemia in our patient.
摘要
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