Castello M A, Ragni G, Antimi A, Todini A, Patti G, Lubrano R, Clerico A, Calisti A
Department of Pediatrics, University La Sapienza, Rome, Italy.
Med Pediatr Oncol. 1997 Mar;28(3):213-5. doi: 10.1002/(sici)1096-911x(199703)28:3<213::aid-mpo12>3.0.co;2-f.
A giant cavernous hemangioma of the left arm with severe thrombocytopenia and consumptive coagulopathy was observed in a neonate. Initial treatment with prednisone, platelet transfusions, and clotting replacement failed to control the bleedings. The child was then treated with daily subcutaneous infusions of interferon alpha-2a. Coagulopathy rapidly improved and transfusions were drastically reduced. The hemangioma regressed progressively and disappeared after 4 months of treatment.
一名新生儿被观察到患有左臂巨大海绵状血管瘤，并伴有严重血小板减少症和消耗性凝血病。最初使用泼尼松、血小板输注和凝血替代治疗未能控制出血。随后该患儿接受了每日皮下注射α-2a干扰素的治疗。凝血病迅速改善，输血次数大幅减少。血管瘤逐渐消退，治疗4个月后消失。
