Amacher A L
Childs Brain. 1977;3(5):257-64. doi: 10.1159/000119676.
The clinical course of twins with osteopetrosis has provided a catalogue of the neurological complications that may occur with the disorder. Such a list has not previously been compiled: (1) Hydrocephalus - probably due to outflow obstruction in the posterior fossa. (2) Sagittal sinus thrombosis - due to bony encroachment, or to hematological causes. (3) Exophthalmos - due to bony encroachment in the orbit. (4) Foraminal occlusion at the base of the skull, producing compromise of cranial nerves and vessels. (5) Paraparesis - cause unknown, perhaps due to spinal stenosis. (6) Anemia - myelophthisic, although a hemolytic component due to hypersplenism has been identified, as well.
患有骨质石化症的双胞胎的临床病程呈现出该病症可能出现的一系列神经并发症。此前尚未编制过这样一份清单：（1）脑积水——可能是由于后颅窝流出道阻塞所致。（2）矢状窦血栓形成——由于骨质侵蚀或血液学原因引起。（3）眼球突出——由于眼眶骨质侵蚀所致。（4）颅底孔道闭塞，导致颅神经和血管受压。（5）双下肢轻瘫——病因不明，可能是由于椎管狭窄。（6）贫血——骨髓痨性贫血，不过也已确认存在因脾功能亢进导致的溶血成分。
