Adjou K T, Deslys J P, Demaimay R, Dormont D
Service de Neurovirologie, CEA/CRSSA, DSV/DRM, Fontenay aux Roses, France.
Trends Microbiol. 1997 Jan;5(1):27-31. doi: 10.1016/S0966-842X(97)81771-4.
Amphotericin B (AmB) is one of the rare drugs that affect the course of experimental prion diseases and modify the kinetics of abnormal prion protein accumulation in the central nervous system. Therefore, AmB could be used as a pharmacological tool to contribute to our understanding of the pathogenic mechanisms involved in these neurodegenerative disorders.
两性霉素B（AmB）是少数能影响实验性朊病毒疾病进程并改变中枢神经系统中异常朊病毒蛋白积累动力学的药物之一。因此，AmB可作为一种药理学工具，有助于我们理解这些神经退行性疾病所涉及的致病机制。
