Gandini S, Panicucci F
Electrodiagn Ther. 1977;14(3):99-105.
After a surgery of the theoretical background of iontophoretic technic and the physico-chemical properties of hyaluronidases, a clinical application is presented, based on over 500 hemophilic patients treated percutaneously, in cases both of hemarthrosis and hematomas. The results are presented and discussed. The conclusion is that hyaluronidase iontophoresis is useful and should be performed together with the other measures for the prevention and the treatment of the damages produced by hemorrhages in hemophilic patients.
在介绍了离子导入技术的理论背景和透明质酸酶的物理化学性质后，本文基于对500多名血友病患者经皮治疗关节积血和血肿的临床应用，展示并讨论了结果。结论是透明质酸酶离子导入疗法是有效的，应与其他预防和治疗血友病患者出血所致损伤的措施一起使用。
