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儿童胰岛素依赖型糖尿病的临床诊断。匈牙利儿童糖尿病流行病学小组

[Clinical diagnosis of childhood insulin dependent diabetes mellitus. Hungarian Epidemiological Group for Childhood Diabetes].

作者信息

Soltész G, Györkö B J, Levy-Marchal C

机构信息

Pécsi Orvostudományi Egyetem Gyermekklinika.

出版信息

Orv Hetil. 1997 Jan 5;138(1):7-9.

PMID:9026772
Abstract

The aim of this study was to describe the clinical presentation and severity of the disease at onset in childhood during 1994. Based on the prospective national incidence registry, data were collected (using a modified version of the EURODIAB ACE questionnaire) from all diabetic children diagnosed during a full calendar year (1994). The ascertainment was 91%. Polyuria, polydipsia and weight loss were the most frequent clinical symptoms, but fatigue, abdominal pain and personality changes were also often reported. Almost one quarter of the children presented with diabetic ketoacidosis. There was no correlation between age, duration of symptoms, blood glucose levels and the severity of disease. The unacceptably high incidence of presentation ketoacidosis called for an urgent improvement of the diagnostic acumen of the physicians dealing with children.

摘要

本研究的目的是描述1994年儿童期疾病发病时的临床表现和严重程度。基于前瞻性全国发病率登记处,收集了(使用欧洲糖尿病青少年糖尿病并发症研究问卷的修改版)全年(1994年)诊断出的所有糖尿病儿童的数据。确诊率为91%。多尿、多饮和体重减轻是最常见的临床症状,但疲劳、腹痛和性格改变也经常被报告。近四分之一的儿童出现糖尿病酮症酸中毒。年龄、症状持续时间、血糖水平与疾病严重程度之间没有相关性。糖尿病酮症酸中毒的高发病率令人无法接受,这就要求紧急提高治疗儿童疾病的医生的诊断敏锐度。

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Orv Hetil. 1997 Jan 5;138(1):7-9.
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引用本文的文献

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Variation between countries in the frequency of diabetic ketoacidosis at first presentation of type 1 diabetes in children: a systematic review.各国儿童 1 型糖尿病初诊时糖尿病酮症酸中毒频率的差异:系统评价。
Diabetologia. 2012 Nov;55(11):2878-94. doi: 10.1007/s00125-012-2690-2. Epub 2012 Aug 30.