[基辅市供体中组织相容性抗原的分布情况]
[The distribution of histocompatibility antigens among donors (the city of Kiev)].
作者信息
Pavliuk R P, Gordienko A I, Kritskaia O E, Vitovskaia O P, Turos E I, Timchenko O I
出版信息
Tsitol Genet. 1996 Sep-Oct;30(5):66-70.
It was shown that the most frequent HLA antigens among Kiev residents are: in the locus A--antigen A2 (36.33%), A1 (25.0%), in the locus B--B8 (20.33%), B13 (17.33%), in the locus C--CW4 (18.0%) and CW2 (12.33%). The frequency of B5 antigen decreased from 26.67 to 11.67% and B12 antigen from 30.33 to 10.67% for the last 10 years. These data may be used as a control for to study the association of histocompatibility antigen system with the human pathology and for the formation of risk groups at some diseases.
结果表明，基辅居民中最常见的HLA抗原为：A位点——抗原A2（36.33%）、A1（25.0%）；B位点——B8（20.33%）、B13（17.33%）；C位点——CW4（18.0%）和CW2（12.33%）。在过去10年中，B5抗原的频率从26.67%降至11.67%，B12抗原的频率从30.33%降至10.67%。这些数据可作为对照，用于研究组织相容性抗原系统与人类病理的关联，以及在某些疾病中形成风险组。
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