Vega S F, Scola B, Vega M F, Martinez T, Scola E
Reparto ORL, Ospedale Generale Universitario Gregorio Maranon, Madrid.
Acta Otorhinolaryngol Ital. 1996 Jun;16(3):272-80.
We present the results of a retrospective study of 467 patients treated with conservative surgery for glottic carcinomas at the ENT department of the "Gregorio Maranon" Hospital between 1962-1993. The disease was staged using the criteria set forth in 1988 by the AJCC, and 27.7% patients were intermediate to advanced stages. Our theoretic treatment protocol is presented. The 5 years uncorrected actuarial survival related to stage was 85.6%, 71.4% and 71% for stages I, II and III respectively. In stages I and II local failure occurred in 22.4% when patients were treated by laryngofisure and 10.8% when treated with hemilaryngectomy. The 5 years local control related to stage was 92.6%, 81.72% and 73.24% for stages I, II and III respectively. In stages I and II the 5 years survival with voice was 75.2% when the patients were treated with radiotherapy and 84.9% when treated with partial laryngectomy. Functional results have been evaluated according to a three grade scale. Good and fair results were 91.1% for the quality of voice, 99.7% for swallowing and 97.6% for respiration.
我们呈现了一项回顾性研究的结果，该研究针对1962年至1993年间在“格雷戈里奥·马拉尼翁”医院耳鼻喉科接受声门癌保守手术治疗的467例患者。疾病分期采用美国癌症联合委员会（AJCC）1988年制定的标准，27.7%的患者处于中期至晚期阶段。我们展示了理论治疗方案。与分期相关的5年未校正精算生存率，I期、II期和III期分别为85.6%、71.4%和71%。在I期和II期，当患者接受喉裂开术治疗时局部失败发生率为22.4%，接受半喉切除术治疗时为10.8%。与分期相关的5年局部控制率，I期、II期和III期分别为92.6%、81.72%和73.24%。在I期和II期，接受放疗的患者5年有声音的生存率为75.2%，接受部分喉切除术的患者为84.9%。根据三级量表对功能结果进行了评估。声音质量的良好和中等结果为91.1%，吞咽为99.7%，呼吸为97.6%。
