Pouchot J, Grasland A, Collet C, Coste J, Esdaile J M, Vinceneux P
Hôpital Louis Mourier, Colombes, France.
Ann Intern Med. 1997 Feb 1;126(3):210-4. doi: 10.7326/0003-4819-126-3-199702010-00005.
Important management decisions depend on results of the tuberculin skin test. However, the test is subject to several potential errors, and its reliability has not been adequately studied.
To ascertain the reliability of tuberculin skin testing.
Cross-sectional study.
University hospital.
96 persons who received a tuberculin skin test.
Ballpoint-pen and palpation measures of induration.
Global intra- and interobserver reliability coefficients of the ballpoint-pen technique were high. Five percent of the time, however, a second measurement by the same observer could be at least 2.7 mm less to 3.0 mm more than the first measurement and the measurement from the second observer could be at least 3.4 mm less to 3.7 mm more than the measurement from the first observer. This could lead to the reclassification of a positive test result as negative or vice versa. The area of imprecision was 38% less broad for the ballpoint-pen technique than for the palpation technique.
Reading of tuberculin skin tests may frequently result in misclassifications when measurements are close to the cutoff point that separates negative from positive results.
重要的管理决策取决于结核菌素皮肤试验的结果。然而，该试验存在一些潜在误差，其可靠性尚未得到充分研究。
确定结核菌素皮肤试验的可靠性。
横断面研究。
大学医院。
96名接受结核菌素皮肤试验的人。
用圆珠笔和触诊法测量硬结。
圆珠笔技术在观察者内和观察者间的总体可靠性系数较高。然而，同一观察者进行的第二次测量有5%的可能性比第一次测量至少少2.7毫米至多3.0毫米，而第二位观察者的测量结果可能比第一位观察者的测量结果至少少3.4毫米至多3.7毫米。这可能导致将阳性试验结果重新分类为阴性，反之亦然。圆珠笔技术的不精确范围比触诊技术窄38%。
当测量结果接近区分阴性和阳性结果的临界点时，结核菌素皮肤试验的判读可能经常导致错误分类。
