Chelmow D, Halfin V P
Department of Obstetrics and Gynecology, Tufts University School of Medicine, Boston, Massachusetts, USA.
J Matern Fetal Med. 1997 Jan-Feb;6(1):31-4. doi: 10.1002/(SICI)1520-6661(199701/02)6:1<31::AID-MFM6>3.0.CO;2-T.
Obsessive-compulsive disorder (OCD) is a well-recognized psychiatric disorder often beginning in reproductive age. A case of OCD in pregnancy is presented and its management discussed. A 28-year-old G3P2 woman presented at 8 weeks' gestation for prenatal care. She had been diagnosed with OCD following her prior pregnancy. Her symptoms primarily involved obsessions about infectious disease and compulsive cleaning and organization of household items, both of which greatly distressed her and interfered with caring for her children. She had been managed with clomipramine between pregnancies and was beginning a clinical trial of fluvoxamine when pregnancy was diagnosed. She discontinued medication when she realized she was pregnant. Her symptoms were managed during the pregnancy with frequent appointments with her obstetrician and her psychiatrist. She used a behavioral technique, "thought-stopping", as well. Her symptoms worsened in the last month of pregnancy and immediately after delivery; she delivered a normal infant. The clomipramine was restarted postpartum. She has done well since then, with minimal psychiatric symptoms. OCD is a disabling psychiatric disorder that occurs in women of reproductive age. With careful management, pregnancy without disabling psychiatric symptoms can occur.
强迫症(OCD)是一种公认的精神障碍,通常始于育龄期。本文介绍了一例妊娠期强迫症病例并讨论了其治疗方法。一名28岁、孕3产2的女性在妊娠8周时前来进行产前检查。她在前次妊娠后被诊断为强迫症。她的症状主要包括对传染病的强迫观念以及对家居用品的强迫性清洁和整理,这两者都极大地困扰着她并干扰了她照顾孩子。她在两次妊娠期间一直服用氯米帕明治疗,在确诊妊娠时正在开始氟伏沙明的临床试验。当她意识到自己怀孕后就停止了用药。在孕期,她通过频繁预约产科医生和精神科医生来控制症状。她还采用了一种行为技巧“思维阻断法”。她的症状在妊娠最后一个月及产后立即加重;她产下一名正常婴儿。产后重新开始服用氯米帕明。从那以后她情况良好,精神症状轻微。强迫症是一种发生在育龄期女性中的致残性精神障碍。通过精心管理,可以实现无致残性精神症状的妊娠。