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丹尼-布朗藏品的利用:广泛单侧脑损伤后前肢和后肢迈步的差异恢复

Utilization of the Denny-Brown collection: differential recovery of forelimb and hind limb stepping after extensive unilateral cerebral lesions.

作者信息

Vilensky J A, Gilman S, Dunn E A, Wilson W J

机构信息

Department of Anatomy, Indiana University School of Medicine, Fort Wayne 46805, USA.

出版信息

Behav Brain Res. 1997 Jan;82(2):223-33. doi: 10.1016/s0166-4328(97)80992-8.

DOI:10.1016/s0166-4328(97)80992-8
PMID:9030404
Abstract

The Denny-Brown collection of primate lesion material was used to test the hypothesis that there is a difference in the rate of forelimb and hind limb recovery of locomotor movements after major unilateral cerebral ablation (pre/postcentral gyrus, decortication or hemispherectomy). The results indicate that, following major cerebral injury, hind limb recovery precedes that of the forelimb in adolescent and adult primates, but not in infants. This suggests that there is an underlying physiological basis to the widely-held belief that, in humans, lower limb recovery after stroke is generally more complete than that of the upper limb.

摘要

丹尼-布朗(Denny-Brown)的灵长类动物损伤材料收集用于检验以下假设:在进行重大单侧脑切除(中央前/后回、去皮质或大脑半球切除术)后,前肢和后肢运动恢复的速度存在差异。结果表明,在遭受重大脑损伤后,青少年和成年灵长类动物的后肢恢复先于前肢,但婴儿并非如此。这表明,人们普遍认为在人类中,中风后下肢恢复通常比上肢更完全,这一观点存在潜在的生理基础。

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