Kharazia V N, Petrusz P, Usunoff K, Weinberg R J, Rustioni A
Department of Cell Biology and Anatomy, University of North Carolina, Chapel Hill 27599, USA.
Brain Res. 1997 Jan 2;744(1):151-5. doi: 10.1016/s0006-8993(96)01105-5.
Simultaneous immunocytochemical staining for arginine (Arg) and histochemical staining for reduced nicotinamide adenine dinucleotide phosphate diaphorase (NADPHd, a marker for nitric oxide synthase) reveals that neuropil in the ventroposterior nucleus of the thalamus is enriched with both Arg-positive glial profiles and NADPHd-positive fibers. NADPHd-positive fibers are often apposed to Arg-positive astrocytes and oligodendrocytes. NADPHd-positive endothelial cells are often adjacent to Arg-positive astrocytes. The results suggest that Arg may be stored in supporting cells, whence it could be supplied to nearby nerve fibers or endothelial cells as substrate for nitric oxide synthase.
对精氨酸（Arg）进行免疫细胞化学同步染色，以及对还原型烟酰胺腺嘌呤二核苷酸磷酸黄递酶（NADPHd，一氧化氮合酶的标志物）进行组织化学染色，结果显示，丘脑腹后核中的神经纤维网富含Arg阳性的神经胶质细胞形态以及NADPHd阳性的纤维。NADPHd阳性纤维常与Arg阳性星形胶质细胞和少突胶质细胞相邻。NADPHd阳性内皮细胞常与Arg阳性星形胶质细胞相邻。结果表明，精氨酸可能储存于支持细胞中，由此它可以作为一氧化氮合酶的底物被供应给附近的神经纤维或内皮细胞。
