Spijkerboer A M, Beek F J, Graaf Y, Eikelboom B C, Mali W P
Department of Radiology, University Hospital Utrecht, Heidelberglaan 100, NL-3584 CX Utrecht, The Netherlands.
Cardiovasc Intervent Radiol. 1997 Mar-Apr;20(2):98-102. doi: 10.1007/s002709900114.
To assess the predictive value of immediate angiographic results after percutaneous transluminal angioplasty (PTA) for stenoses in femoral bypass grafts using duplex ultrasound (DUS) criteria.
A 1-year follow-up with DUS was performed in 38 patients with 50 stenoses in 41 grafts, treated with PTA for a graft stenosis. The indication for PTA according to DUS criteria was a severe stenosis in 43 lesions, and a moderate stenosis in 7 lesions. In the moderate stenosis group 3 patients showed claudication and 1 patient had a nonhealing ulcer. For the purposes of statistical evaluation, primary patency was considered present if the graft was not occluded. The graft was considered to have failed when it was found to be occluded on DUS, or when secondary interventions (surgery, repeat PTA) were performed.
After 1 year the cumulative primary patency rate was 44% [95% confidence interval (CI) 27.8-59.8]. Stenoses with initially good angiographic results after PTA (< 30% residual stenosis) were 2.9 times more likely to be patent at 1 year than stenoses with initially poor or moderate angiographic results (hazard ratio 2.9, 95% CI 1.3-6.4, p = 0.007).
A poor or moderate angiographic result immediately following PTA was prognostic for poor long-term results and may indicate a requirement for earlier surgical intervention.
使用双功超声(DUS)标准评估经皮腔内血管成形术(PTA)后即刻血管造影结果对股动脉搭桥移植物狭窄的预测价值。
对41条移植物中存在50处狭窄的38例患者进行了为期1年的DUS随访,这些患者因移植物狭窄接受了PTA治疗。根据DUS标准,PTA的指征为43处病变为重度狭窄,7处病变为中度狭窄。在中度狭窄组中,3例患者出现间歇性跛行,1例患者有不愈合溃疡。为进行统计学评估,如果移植物未闭塞,则认为存在原发性通畅。当在DUS上发现移植物闭塞,或进行了二次干预(手术、重复PTA)时,则认为移植物失败。
1年后累积原发性通畅率为44%[95%置信区间(CI)27.8 - 59.8]。PTA后最初血管造影结果良好(残余狭窄<30%)的狭窄在1年时通畅的可能性是最初血管造影结果较差或中等的狭窄的2.9倍(风险比2.9,95%CI 1.3 - 6.4,p = 0.007)。
PTA后即刻血管造影结果较差或中等预示着长期结果不佳,可能表明需要更早进行手术干预。