Wacker F K, Boese-Landgraf J, Wagner A, Albrecht D, Wolf K J, Fobbe F
Department of Radiology, Benjamin Franklin University Hospital, Free University Berlin, Hindenburgdamm 30, D-12200 Berlin, Germany.
Cardiovasc Intervent Radiol. 1997 Mar-Apr;20(2):128-32. doi: 10.1007/s002709900120.
Development of a percutaneously implantable catheter system for regional chemotherapy of liver metastases and its application in patients with surgically implanted but dislocated catheters.
Thirty-three patients with liver metastases of colorectal tumors were submitted to percutaneous puncture of the subclavian artery and insertion of a catheter whose tip was placed in the proper hepatic artery and whose end was subcutaneously connected with an infusion pump.
The mean duration of therapy via the percutaneously inserted catheter was 27 weeks (+/-14 weeks). The most frequent complication was disconnection of the therapy catheter from the tube of the infusion pump. Eighty percent of all complications were corrected by reintervention. The therapy drop-out rate due to catheter-associated complications was 9%.
Percutaneous insertion of a catheter for regional chemotherapy of the liver is a relatively uncomplicated method with high patient acceptance and simple access for reintervention.
研发一种用于肝转移瘤区域化疗的经皮植入式导管系统，并将其应用于手术植入但发生移位的导管患者。
33例结直肠肿瘤肝转移患者接受锁骨下动脉经皮穿刺，并插入一根导管，导管尖端置于肝固有动脉，其末端与皮下输液泵相连。
经皮插入导管的平均治疗时间为27周（±14周）。最常见的并发症是治疗导管与输液泵管断开连接。所有并发症的80%通过再次干预得到纠正。因导管相关并发症导致的治疗中断率为9%。
经皮插入导管进行肝脏区域化疗是一种相对简单的方法，患者接受度高，再次干预的途径简便。
