Ena P, Lissia M, Doneddu G M, Campus G V
Department of Dermatology, Faculty of Medicine, Sassari University, Italy.
Dermatology. 1997;194(1):80-4. doi: 10.1159/000246066.
Three patients developed erosive pustular dermatosis of the scalp (EPDS). Two of them, both males, had previously undergone surgical excision for squamous cell carcinoma and basal cell carcinoma, and a female experienced avulsive trauma of the scalp. The erosive lesions and crusts were located at the site of a skin graft; microbiological cultures were negative for bacterial and fungal growth. Histological examination ruled out pustular bullous disorders. Topical therapy with corticosteroids and antibiotics resulted in clinical remission in only 2 cases. The third case showed a tendency to recur despite numerous therapeutic attempts with oral dapsone and isotretinoin. We conclude that surgical trauma is a possible cause of EPDS. Our patients seem to be the first reported cases of EPDS in skin grafts following plastic surgical procedures.
三名患者出现了头皮糜烂性脓疱性皮炎（EPDS）。其中两名男性患者之前因鳞状细胞癌和基底细胞癌接受过手术切除，一名女性患者经历了头皮撕脱伤。糜烂性病变和痂皮位于皮肤移植部位；细菌和真菌培养的微生物学检查结果均为阴性。组织学检查排除了脓疱性大疱性疾病。仅2例患者通过局部使用皮质类固醇和抗生素治疗后实现了临床缓解。尽管对第三例患者多次尝试口服氨苯砜和异维A酸治疗，但仍有复发倾向。我们得出结论，手术创伤是EPDS的一个可能病因。我们的患者似乎是首例报道的整形手术后皮肤移植部位发生EPDS的病例。
