Joseph T, Hiltgen M, Gaulier A, Saudemont J P
Service de Cardiologie, Hôpital V. Dupouy, Argenteuil.
Ann Cardiol Angeiol (Paris). 1996 Dec;45(10):581-4.
Myocardial infarction is not exceptional in patients with essential thrombocythaemia. This infarction is often related to the formation of in situ coronary thrombosis with no associated atheromatous lesions. The authors report the case of a thrombocythaemic patient with anterior infarction due to thrombosis of the left coronary artery. The clinical course is often more severe than in nonthrombocythaemic patients. The pathophysiological mechanisms remain unclear, but appear to be related to qualitative rather than quantitative platelet abnormalities.
原发性血小板增多症患者发生心肌梗死并不罕见。这种梗死通常与原位冠状动脉血栓形成有关，而无相关动脉粥样硬化病变。作者报告了一例因左冠状动脉血栓形成导致前壁梗死的血小板增多症患者。其临床病程往往比非血小板增多症患者更为严重。病理生理机制尚不清楚，但似乎与血小板的质量异常而非数量异常有关。
