[慢性淋巴细胞白血病中的副肿瘤性天疱疮]
[Paraneoplastic pemphigus in chronic lymphocytic leukemia].
作者信息
Fournier B, Bouscarat F, Le Bozec P, Joly P, Gardin P, Grossin M, Descamps V, Crickx B, Belaïch S
机构信息
Service de Dermatologie, Hôpital Bichat, Paris.
出版信息
Ann Dermatol Venereol. 1996;123(8):483-6.
INTRODUCTION
Paraneoplastic pemphigus is an autoimmune bullous disease described by precise clinical, histological and immunological features presented by Anhalt in 1990. Prognosis is very severe and depends on the associated neoplasia and the gravity of the mucosal damage.
CASE REPORT
Paraneoplastic pemphigus was diagnosed in a 62-year-old man with chronic lymphoid leukemia. The course was favorable up to one-year follow-up after general corticosteroid therapy.
DISCUSSION
This case illustrates that paraneoplastic pemphigus can be controlled by general corticosteroids and would suggest the severe prognosis may be improved.
引言
副肿瘤性天疱疮是一种自身免疫性大疱性疾病，由安哈尔特于1990年描述，具有精确的临床、组织学和免疫学特征。预后非常严重，取决于相关的肿瘤以及黏膜损伤的严重程度。
病例报告
一名62岁慢性淋巴细胞白血病男性被诊断为副肿瘤性天疱疮。在接受全身皮质类固醇治疗后的一年随访中，病情进展良好。
讨论
该病例表明，副肿瘤性天疱疮可以通过全身皮质类固醇得到控制，这可能提示严重的预后情况会有所改善。
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