Donnet A, Gouirand R, Zandotti C, Grisoli F
Service de Neurochirurgíe, CHU Timone-Marseille, France.
Rev Neurol (Paris). 1996 Oct;152(10):640-1.
Cytomegalovirus encephalitis in immunologically normal patients is rarely reported in the literature. Only seven cases have been previously reported. CMV infection was diagnosed in a 24-year-old, immunologically normal female presenting a severe clinical picture due to encephalitis. Diagnosis was based on detection of CMV DNA in the CSF with the polymerase chain reaction. Administration of ganciclovir was followed by an immediate improvement.
免疫功能正常患者的巨细胞病毒性脑炎在文献中鲜有报道。此前仅报告过7例。一名24岁免疫功能正常的女性因脑炎出现严重临床症状,被诊断为巨细胞病毒感染。诊断依据是通过聚合酶链反应在脑脊液中检测到巨细胞病毒DNA。给予更昔洛韦治疗后症状立即改善。