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月度病例。1996年7月——性早熟。

Case of the month. July 1996--precocious puberty.

作者信息

Hamilton R L

机构信息

University of Pittsburgh School of Medicine, Division of Neuropathology, PA, USA.

出版信息

Brain Pathol. 1997 Jan;7(1):711-2. doi: 10.1111/j.1750-3639.1997.tb01085.x.

Abstract

A 4 year old girl presented with precocious puberty. She had pubic hair, breast buds and showed a height and weight well above the 95th percentile. An MRI scan of the head revealed a discrete mass in the tuber cinereum which was surgically removed. Microscopic examination showed a hypothalamic hamartoma. The clinical, radiologic and microscopic findings in this case are "classic" for hypothalamic hamartoma Other clinical presentations are discussed. The patient's symptoms have regressed following surgery and there has been no regrowth in six months.

摘要

一名4岁女孩出现性早熟。她有阴毛、乳房芽,身高和体重远高于第95百分位。头部MRI扫描显示灰结节有一个离散肿块,已通过手术切除。显微镜检查显示为下丘脑错构瘤。该病例的临床、放射学和显微镜检查结果是下丘脑错构瘤的“典型”表现。还讨论了其他临床表现。患者术后症状已消退,六个月内未再生长。

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