Evaluation of some acylamide derivatives as potential hypoglycemic agents.
作者信息
Srivastava V, Suresh A J, Pandeya S N, Pandey A
机构信息
Dept. of Pharmaceutics, I.T., Varanasi, India.
出版信息
Boll Chim Farm. 1996 Jul-Aug;135(7):452-7.
PMID:9035557
Abstract
A series of new acylamide derivatives with piperidine, pyrrolidinyl and alanyl have been tested for their hypoglycemic activities. 2-(Pyrrolidynyl)-N-(3-chlorophenyl) acetamide and 2-(Piperazinyl)-N-(4-methoxy phenyl) acetamide were found most active hypoglycemic compounds. Probably the amides have mode of action similar to sulphonylureas.
摘要
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