Srivastava V, Suresh A J, Pandeya S N, Pandey A
Dept. of Pharmaceutics, I.T., Varanasi, India.
Boll Chim Farm. 1996 Jul-Aug;135(7):452-7.
A series of new acylamide derivatives with piperidine, pyrrolidinyl and alanyl have been tested for their hypoglycemic activities. 2-(Pyrrolidynyl)-N-(3-chlorophenyl) acetamide and 2-(Piperazinyl)-N-(4-methoxy phenyl) acetamide were found most active hypoglycemic compounds. Probably the amides have mode of action similar to sulphonylureas.
