Orlov S N, Novikov K N
Fiziol Zh Im I M Sechenova. 1996 Aug-Sep;82(8-9):1-15.
A review contemplates as a whole the problem of regulation of the cellular volume. The first part of the review considers the influences inducing alterations in the cells volume on account of changes in the tonicity of extracellular milieu and cytoplasm. The review elucidates the ways of implementing the fast and slow regulatory volume increase as well as decrease (RVI, RVD). The volume increase seems to enhance cells' proliferative ability due to activation of ions transport. The volume decrease needs further investigations. The last chapter of the review considers pathophysiological significance of the volume regulation in hyponatremia, diabetes, neutrophil activation.
一篇综述全面探讨了细胞体积调节的问题。该综述的第一部分考虑了由于细胞外环境和细胞质张力变化而导致细胞体积改变的影响因素。该综述阐明了实现快速和缓慢调节性体积增加以及减少(RVI,RVD)的方式。体积增加似乎通过激活离子转运来增强细胞的增殖能力。体积减少则需要进一步研究。该综述的最后一章探讨了在低钠血症、糖尿病、中性粒细胞激活中体积调节的病理生理学意义。